Aminoglycoside-induced hearing deficits – a review of cochlear ototoxicity

  • Lucretia Petersen University of Cape Town
  • Christine Rogers University of Cape Town
Keywords: amikacin, aminoglycosides, cochleotoxicity, hearing loss, kanamycin, ototoxicity

Abstract

This article aims to inform the reader about current knowledge of the effects of aminoglycosides on hearing. The hearing loss caused by aminoglycosides is permanent and can negatively affect the individual’s quality of life. Although treatment with aminoglycosides cannot be avoided in some instances, timely intervention can minimise the impact of the hearing loss on the individual’s everyday life. The discussion includes the incidence of aminoglycoside-induced hearing loss and predisposing factors. In addition, monitoring and management of cochlear ototoxicity is described. (Full text available online at www.medpharm.tandfonline.com/ojfp) S Afr Fam Pract 2015; DOI: 10.1080/20786190.2014.1002220

Author Biographies

Lucretia Petersen, University of Cape Town
MSc Audiology Senior Lecturer Division of Communication Sciences and Disorders University of Cape Town
Christine Rogers, University of Cape Town
University of Cape Town Division of Communication Sciences and Disorders University of Cape Town
Published
2015-05-19
Section
Research Articles