Avian Influenza: What the family practitioner should know

  • M Senekal Clinical Microbiologist, Pathcare Reference Laboratory N1 City, Goodwood
  • E Wasserman Department of Pathology, Chairperson of Discipline Medical Microbiology, NHLS Tygerberg Hospital and University of Stellenbosch

Abstract

Human immunity to influenza A virus depends on the specific subtype. Mortality after exposure to subtypes commonly causing human infection is low (approximately 0.1%). Other subtypes are specifically adapted to cause disease in birds. These subtypes are known as ‘avian influenza’. Under cer t a i n circumstances avian influenza can also be transmitted to humans, causing a severe infection known as highly pathogenic avian influenza (HPAI), with a mortality currently exceeding 50%.
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Review Articles