The medical management of glaucoma

  • André Marais University of Pretoria
  • Elzbieta Osuch Sefako Makghato Health Sciences University
Keywords: Glaucoma, prostaglandin analogs, carbonic anhydrase inhibitors, beta antagonists, alpha 2 adrenergic agonists, cholinergic agonists

Abstract

Glaucoma is one of the leading causes of blindness worldwide. The main characteristic features include optic disc cupping, visual field loss, and in most instances a raised intraocular pressure. Primary open angle glaucoma accounts for nearly two thirds of all cases, while angle closure glaucoma contributes the majority of the remainder. Screening for glaucoma is not cost-effective, and diagnosis of the primary open angle type is usually an incidental finding during ophthalmological examination. Various treatment options, including medical and surgical interventions are accessible in the management of glaucoma. This article contains a brief description on the pathophysiology and focuses on the pharmacological options available in the treatment of glaucoma.

Author Biographies

André Marais, University of Pretoria
BPharm, MBChB, MSC.Pharm, ACCP(SA) Senior Lecturer and Clinical Pharmacologist Department of Pharmacology School of Medicine Faculty of Health Sciences University of Pretoria
Elzbieta Osuch, Sefako Makghato Health Sciences University
MD, PhD Pharmacology, FCP(ACCP), MSc(Med) Pharmacology, ACCP(SA), Dip Fam Med(Cum Laude) Professor and Clinical Pharmacologist Department of Pharmacology & Therapeutics School of Medicine Sefako Makghato Health Sciences University
Section
Review Articles