Evidence that changes the way you practice: Bipolar Disorder: Mania and depression explained

  • Kim Outhoff University of Pretoria
Keywords: bipolar disorder, mania, depression

Abstract

Bipolar Disorder (BD) is characterised by alternating discrete episodes of depression and mania.1 Rational pharmacotherapy necessitates an appreciation of these different phases and of the possible underlying pathophysiology. A greater understanding of the pathogenesis of BD has boosted awareness of how anti-bipolar drugs work, and vice versa.2 This bidirectional relationship has amplified knowledge in both disciplines.

Author Biography

Kim Outhoff, University of Pretoria
Department of Pharmacology University of Pretoria
Section
Review Articles