Gastro-oesophageal reflux: An overview of the cost-effectiveness of pharmacotherapeutic treatment options

  • Gustav Schellack
  • J C Meyer Sefako Makgatho Health Sciences University
  • Natalie Schellack Sefako Makgatho Health Sciences University
Keywords: GORD, gastro-oesophageal reflux, PPIs, proton-pump inhibitors, cost-effectiveness

Abstract

Gastro-oesophageal reflux disease (GORD) produces symptoms that cause great irritation to the patient. Pharmacotherapeutic management is directed at minimising these symptoms and reducing the causative factors, e.g. acid production, thereby providing relieve. Currently available agents include simple antacids and acid suppression therapy, including histamine 2-receptor antagonists, proton pump inhibitors, mucosal or cytoprotective agents, pro-motility agents. Deciding on appropriate therapy will be dependent on the diagnosis, side-effects and cost-effectiveness of the treatment.

Author Biographies

Gustav Schellack
BCur, Adv Univ Dipl Nurs Sc (HSM), Hons BSc (Pharmacology) Clinical Research
J C Meyer, Sefako Makgatho Health Sciences University
BPharm, MSc (Med) Pharmacy, PhD (Pharmacy) Associate Professor Department of Pharmacy Faculty of Health Sciences Sefako Makgatho Health Sciences University
Natalie Schellack, Sefako Makgatho Health Sciences University
BCur, BPharm, PhD Senior Lecturer Department of Pharmacy Faculty of Health Sciences Sefako Makgatho Health Sciences University
Section
Review Articles