Silodosin — a safer alpha-blocker targeting benign prostatic hyperplasia

  • Karen Koch
Keywords: alpha-1A receptor inhibitor, benign prostatic hypertrophy, BPH, lower urinary tract symptoms


Silodosin is a specific alpha-1A receptor inhibitor newly available in South Africa. It offers a real solution to symptoms of BPH especially in those patients with moderate prostate enlargement experiencing nocturia, frequency and incomplete voiding. It can be safely used in patients who cannot tolerate non-selective alpha blockers. The main side-effect is anejaculation, but this seldom leads to drug discontinuation. The rapid action and ongoing effectiveness of the drug offers swift relief for patients. (Full text available online at S Afr Fam Pract 2015; DOI: 10.1080/20786190.2014.978099

Author Biography

Karen Koch
Private practice GP and freelance medical writer Mediscribe Medical Writing Johannesburg South Africa
Research Articles