The Mystique of Migraine Part IV: Is it in the blood?

  • Prof RJE Henbest Medunsa
Keywords: Migraine, Etiology, Blood Platelets, Physicians, Family.

Abstract

This paper is the fourth in a series on migraine. The first concerned the nature and diagnosis of migraine. Subsequent papers addressed questions about its aetiology, beginning with, "Is it vascular?", followed by "Is it neurogenic?". This paper presents a humoral theory, describes the platelet abnormalities and disturbances in 5-hydroxytriptramine ( 5 -HT, serotonin) levels that occur with migraine, reviews the anti-migraine drugs that interact with 5-HT receptors and considers the possibility of migraine being an endotheliopathy.

Author Biography

Prof RJE Henbest, Medunsa
MD, CCFP, MCISc (Fam Med) The Dept of Family Medicine
Section
Review Articles