Cholera - The Grim Reality of Under-development

  • DN Durrheim Communicable Disease Control
  • GA Ogunbanjo Medunsa
  • L Blumberg University of theWitwatersrand
  • KH Keddy University of the Witwatersrand
Keywords: Vibrio cholerae, cholera, diagnosis, rehydration, multidrug resistance, vaccination

Abstract

Cholera is a severe diarrhoeal illness caused by certain strains of Vibrio cholerae, which can lead rapidly to dehydration and death. Communities dependent on water contaminated with human faeces and those with poor sanitation are very vulnerable to cholera epidemics. Although theVibrio cholerae Ol El Tor strain presently circulating in southern Africa is multi-drug resistant and currently available vaccines offer inadequate proteccion, cholera can be pre-vented by simple cost-effective measures, including chlorination or sustained boiling of drinking water. The key to cholera management is aggressive fluid replacement with the correct fluids. The latter strategy is so effective that a cholera death may be viewed as a health system failure deserving formal review. The only sustainable solution to the scourge of cholera is fundamental economic and social development with the provision of safe water and adequate sanitation for all communities.

Author Biographies

DN Durrheim, Communicable Disease Control
MB, ChB, DTM&H, DCH, FACTM, MPH &TM Mpumalanga Department of Health, Nelspruit
GA Ogunbanjo, Medunsa
MB, BS, MFGP (SA), MFamMed (MEDUNSA) Department of Family Medicine & Primary Health Care, Pretoria
L Blumberg, University of theWitwatersrand
MB, BCh, DTM&H, DOH, DCH Dept. of Clinical Microbiology & Infectious Diseases, South African lnstitute for Medical Research
KH Keddy, University of the Witwatersrand
BSc (Med), MB BCh, DTM&H, FRCPath (SA), MMed Dept. of Clinical Microbiology & lnfectious Diseases, South African lnstitute for Medical Research
Section
Original Research