Evidence for Zolpidem efficacy in brain damage.

  • RP Clauss Nuclear Medicine Department, Royal Surrey County Hospital, Guildford, Surrey, GU2 7XX, United Kingdom.
  • H W Nel Family Practice, 9 Media Road, Pollack Park, Springs, South Africa

Abstract

Previous reports have shown that zolpidem could reverse semi-coma and improve cerebral perfusion after brain injury. Studies in animals have implicated omega 1 GABAergic action as reason for this improvement. Evidence for the efficacy of zolpidem in a wide range of brain pathology is reviewed here and the mechanism of zolpidem in brain injury is considered from the perspective of diaschisis and neurological dormancy after brain injury. (SA Fam Pract 2005;47(3): 49-50)

Author Biographies

RP Clauss, Nuclear Medicine Department, Royal Surrey County Hospital, Guildford, Surrey, GU2 7XX, United Kingdom.
MBChB, M. Med. (Nuc.Med.), MD.
H W Nel, Family Practice, 9 Media Road, Pollack Park, Springs, South Africa
MBChB.
Published
2005-04-01
Issue
Vol 47, No 3 - April 2005
Section
Case studies
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