Immune Evaluation of HIV-Infected and Noninfected Pre-Eclamptics

  • Kalendri Naidoo Centre for the AIDS Programme Research in South Africa (CAPRISA), University of KwaZulu-Natal
  • Xanti Pupuma Department of Obstetrics and Gynaecology, University of KwaZulu-Natal
  • Jagidesa Moodley Nelson R Mandela School of Medicine
Keywords: HIV , HIV-, pre-eclampsia, haematological

Abstract

It is widely known that an individual’s immune status is debilitated by HIV infection. In the early stages of HIV infection, when few symptoms are seen, there may be a slight depression in CD4 T cells, which is temporary at this stage. Immune abnormalities appear during the second stage, when the virus begins to replicate rapidly, which results in a decrease in the percentage and total number of CD4 T cells. The decrease in CD4 T cells remains the most widely used parameter to assess disease progression.
Published
2009-11-22
Section
Scientific letters